SCEA Probit Analysis
Dose-Response Modeling & Potency Estimation
A professional-grade experimental tool designed for modeling dose-response relationships in toxicology, pharmacology, and biological assays. Determine critical values like $LD_{50}$ with journal-grade precision.
Linearized Probit Regression & Sigmoid Curves.
The SCEA Probit suite provides a specialized environment to determine how a specific dose correlates with a binary outcome. It features dual-chart visualization: a Linear Regression Plot for model fit validation and a Sigmoid S-Curve for actual probability visualization.
Core Capabilities
Potency Thresholds
Automatically calculates critical lethal dose values such as $LD_{50}$, $LD_{90}$, and $LD_{99}$ with confidence intervals.
Weighted Regression
Utilizes a weighted engine approximating MLE to handle high variance found at the extreme tails of distribution.
Dual-Chart Plotting
Toggle between linearized Probit-Dose plots and sigmoid probability curves for comprehensive assay inspection.
Professional Export
Generate high-density metric cards and export results directly as PDF, DOCX, or JSON for research inclusion.
How to Operate
Input your dose levels and observed responses (total vs. responded). Select your preferred transformation (Log10, LN, or Linear).
Verify the linearized regression fit. The suite uses weighted calculations to account for variances at dose extremes.
Review the potency metrics and sigmoid curve. Export the complete report for direct use in pharmacological papers.
Modeling dose-response relationships with professional-grade precision.